Clinical Trials

Carolinas Centers for Sight physicians are committed to participating in clinical research studies designed to improve therapies for many types of eye diseases.

Here are the clinical trials in which we are currently involved:

1.  Protocol: SCORE2 Sponsor: The EMMES Corporation

Study of COmparative Treatments for REtinal Vein Occlusion 2 [SCORE2]: a multicenter, prospective, randomized non-inferiority trial of eyes with macular edema secondary to central retinal vein occlusion, comparing Intravitreal Bevacizumab every 4 weeks with Intravitreal Aflibercept every 4 weeks.

Enrollment is closed

2. Protocol: R2176-3-AMD-1417 (CAPELLA) Sponsor: Regeneron

A Phase 2, Double-Masked, Randomized, Controlled, Multiple-Dose, Regimen-Ranging Study of the Efficacy and Safety of Invtravitreal REGN2176-3 in Patients with Neovascular Age-Related Macular Degeneration

Enrollment is closed

3. Protocol: VGFTe-OD-1411 (PANORAMA) Sponsor: Regeneron

A Phase 3, Double-Masked, Randomized Study of the Efficacy and Safety of Intravitreal Aflibercept Injection in Patients with Moderately Severe to Severe Nonproliferative Diabetic Retinopathy

*Currently enrolling patients

4. Protocol: R910-3-DME-1518 (RUBY) Sponsor: Regeneron

A Randomized, Double-Masked, Active-Controlled Phase 2 Study of the Efficacy, Safety, and Tolerability of Repeated Doses of Intravitreal REGN910-3 in Patients with Diabetic Macular Edema

*Currently enrolling patients

5. Protocol: AR-13324-CS304 Sponsor: Aerie Pharmaceuticals, Inc.

A double-masked, randomized, multi-center, active-controlled, parallel group, 6-month study with a 3-month interim analysis assessing the ocular hypotensive efficacy and safety of AR-13324 Ophthalmic Solution, 0.02% QD compared to Timolol Maleate Ophthalmic Solution, 0.5% BID in patients with elevated intraocular pressure

Enrollment is closed

For further information regarding Clinical Research at Carolinas Centers for Sight, P.C., contact us at 843.664.9393.

Lasik3

CATARACT
Self-Evaluation

Dry Eyes3

DRY EYE
Self-Evaluation

Cataract3

LASIK
Self-Evaluation

Lasik3

Reading Vision
Evaluation